Well, saying I do to your career that is. There are certain things to consider before you agree to taking a job. And while this article from LearnVest has some great things to consider – salary, commute, timing, etc. It is always important to know what is important to you and what your bottom line will be. It’s important to know what you value, not only in your job, but in your life. It’s important that you can get along with your co-workers, whatever “get along” means to you. Some people walk into a research lab and get annoyed that people aren’t chatty and know everything about their co-work lives. Others hate knowing all the intimate details of people’s lives. You have to know what you value in your work life.
And know that it will change. You will learn that you love and hate different things. You will learn about different environments and different people. You will learn about different jobs and duties.
TL;DR it’s important to know what you value when saying “I do” to your new career.